CMap Candidate Details

Structure:
CMap ID: C11550
Pert ID: BRD-K28907958
Compound Name: CD-437
Targets: RARG
MoA: Retinoid receptor agonist
SMILES: OC(=O)c1ccc2cc(ccc2c1)-c1ccc(O)c(c1)C12CC3CC(CC(C3)C1)C2
InchiKey: LDGIHZJOIQSHPB-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
8929 BRD-K28907958 A375 12 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
9401 BRD-K28907958 AGS 12 uM 6 h -0.27 -1.12 0.39 0.0 0.0 0.0
9711 BRD-K28907958 H1299 12 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10051 BRD-K28907958 HA1E 12 uM 6 h -0.19 -0.79 0.0 0.0 0.0 0.0
10368 BRD-K28907958 HCC515 12 uM 6 h 0.0 0.0 0.0 -0.48 -1.6 15.65
10496 BRD-K28907958 HCT116 12 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10769 BRD-K28907958 HEPG2 12 uM 6 h 0.0 0.0 0.0 -0.3 -1.01 0.56
11119 BRD-K28907958 HT29 12 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
11277 BRD-K28907958 MCF??7.00 12 uM 6 h -0.28 -1.16 0.45 0.0 0.0 0.0
11463 BRD-K28907958 NCIH2073 12 uM 6 h -0.18 -0.74 0.0 0.0 0.0 0.0
11744 BRD-K28907958 NCIH508 12 uM 6 h 0.24 0.98 0.09 0.0 0.0 0.0
12027 BRD-K28907958 NCIH596 12 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12297 BRD-K28907958 NOMO1 12 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12602 BRD-K28907958 PC3 12 uM 6 h -0.31 -1.28 0.77 0.0 0.0 0.0
13112 BRD-K28907958 THP1 12 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
13251 BRD-K28907958 U937 12 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
13607 BRD-K28907958 VCAP 12 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
90557 BRD-K28907958 A549 4 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
96009 BRD-K28907958 PHH 1.11 uM 24 h -0.2 -0.85 0.01 0.18 0.65 0.01
99806 BRD-K28907958 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).