CMap Candidate Details

Structure:
CMap ID: C11576
Pert ID: BRD-K28965160
Compound Name: BVD-523
Targets: --
MoA: --
SMILES: CC(C)Nc1cc(-c2c[nH]c(c2)C(=O)N[C@H](CO)c2cccc(Cl)c2)c(Cl)cn1
InchiKey: KSERXGMCDHOLSS-LJQANCHMSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
121888 BRD-K28965160 A375 1.11 uM 24 h 0.0 0.0 0.0 -0.26 -0.87 0.23
121934 BRD-K28965160 HA1E 10 uM 24 h 0.24 0.99 0.09 -0.27 -0.91 0.3
121979 BRD-K28965160 HELA 3.33 uM 24 h 0.33 1.36 0.97 0.3 1.05 0.56
122004 BRD-K28965160 HT29 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122040 BRD-K28965160 HUVEC 3.33 uM 24 h 0.0 0.0 0.0 -0.27 -0.9 0.29
122088 BRD-K28965160 MCF10A 10 uM 24 h 0.18 0.74 0.0 0.0 0.0 0.0
122135 BRD-K28965160 MDAMB231 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122160 BRD-K28965160 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122186 BRD-K28965160 THP1 3.33 uM 24 h 0.0 0.0 0.0 -0.26 -0.88 0.25
122214 BRD-K28965160 YAPC 3.33 uM 24 h 0.0 0.0 0.0 0.26 0.91 0.23
130198 BRD-K28965160 A549 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130252 BRD-K28965160 HEK293 0.01 uM 24 h -0.26 -1.1 0.34 0.0 0.0 0.0
130342 BRD-K28965160 JURKAT 2.22 uM 24 h 0.29 1.21 0.47 0.22 0.78 0.07
130427 BRD-K28965160 MCF??7.00 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).