CMap Candidate Details

Structure:
CMap ID: C11578
Pert ID: BRD-K28971625
Compound Name: ZD-7114
Targets: ADRB3
MoA: Adrenergic receptor agonist
SMILES: COCCNC(=O)COc1ccc(OCCNC[C@H](O)COc2ccccc2)cc1
InchiKey: RVMBDLSFFNKKLG-SFHVURJKSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
119949 BRD-K28971625 A375 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
119991 BRD-K28971625 A549 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120108 BRD-K28971625 HT29 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120150 BRD-K28971625 MCF??7.00 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120188 BRD-K28971625 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
128814 BRD-K28971625 HA1E 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
128829 BRD-K28971625 HELA 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
128873 BRD-K28971625 YAPC 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).