CMap Candidate Details

Structure:
CMap ID: C11633
Pert ID: BRD-K29173907
Compound Name: isoflupredone-acetate
Targets: NR3C1
MoA: Glucocorticoid receptor agonist
SMILES: CC(=O)OCC(=O)[C@@]1(O)CC[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]12C
InchiKey: ZOCUOMKMBMEYQV-GSLJADNHSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1751 BRD-K29173907 HA1E 10 uM 6 h 0.0 0.0 0.0 -0.41 -1.38 2.02
2099 BRD-K29173907 HCC515 10 uM 6 h 0.0 0.0 0.0 -0.31 -1.04 0.67
2192 BRD-K29173907 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
2490 BRD-K29173907 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41759 BRD-K29173907 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
42088 BRD-K29173907 A549 10 uM 6 h 0.21 0.89 0.02 0.0 0.0 0.0
42345 BRD-K29173907 ASC 10 uM 24 h 0.0 0.0 0.0 0.21 0.75 0.04
42671 BRD-K29173907 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
42976 BRD-K29173907 HT29 10 uM 6 h 0.0 0.0 0.0 -0.33 -1.12 0.95
43181 BRD-K29173907 MCF??7.00 10 uM 24 h -0.28 -1.15 0.44 -0.29 -0.98 0.47
43537 BRD-K29173907 NPC 10 uM 24 h -0.22 -0.94 0.08 0.0 0.0 0.0
43834 BRD-K29173907 PHH 10 uM 24 h 0.0 0.0 0.0 0.22 0.78 0.07
44104 BRD-K29173907 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).