CMap Candidate Details

Structure:
CMap ID: C11680
Pert ID: BRD-K29313308
Compound Name: HDAC3-selective
Targets: HDAC3
MoA: HDAC inhibitor
SMILES: CC(=O)Nc1ccc(cc1)C(=O)Nc1ccc(F)cc1N
InchiKey: RRJDFENBXIEAPD-UHFFFAOYSA-N
Compound Aliases: HDAC-3-SELECTIVE

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
90510 BRD-K29313308 HA1E 10 uM 6 h 0.0 0.0 0.0 -0.32 -1.06 0.75
90519 BRD-K29313308 PC3 2.5 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
96209 BRD-K29313308 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
96279 BRD-K29313308 U2OS 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
98567 BRD-K29313308 NEU 10 uM 6 h -0.22 -0.9 0.04 0.0 0.0 0.0
98684 BRD-K29313308 NPC 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
119178 BRD-K29313308 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
119264 BRD-K29313308 HCC515 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
119294 BRD-K29313308 HEPG2 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
119322 BRD-K29313308 HT29 10 uM 24 h 0.0 0.0 0.0 -0.3 -1.01 0.55
119346 BRD-K29313308 MCF??7.00 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).