CMap Candidate Details
Structure:
| CMap ID: | C11683 |
| Pert ID: | BRD-K29322660 |
| Compound Name: | edoxaban |
| Targets: | F10 |
| MoA: | Coagulation factor inhibitor |
| SMILES: | CN(C)C(=O)[C@@H]1CC[C@H](NC(=O)C(=O)Nc2ccc(Cl)cn2)[C@H](C1)NC(=O)c1nc2CCN(C)Cc2s1 |
| InchiKey: | HGVDHZBSSITLCT-KMFMINBZSA-N |
| Compound Aliases: | -- |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 119951 | BRD-K29322660 | A375 | 0.04 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 119993 | BRD-K29322660 | A549 | 0.04 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 120110 | BRD-K29322660 | HT29 | 0.37 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 120152 | BRD-K29322660 | MCF??7.00 | 0.04 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 128815 | BRD-K29322660 | HA1E | 2.22 uM | 24 h | 0.29 | 1.2 | 0.42 | 0.0 | 0.0 | 0.0 |
| 128837 | BRD-K29322660 | HELA | 0.01 uM | 3 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 128849 | BRD-K29322660 | PC3 | 0.74 uM | 24 h | 0.35 | 1.45 | 1.12 | 0.0 | 0.0 | 0.0 |
| 128875 | BRD-K29322660 | YAPC | 0.03 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |