CMap Candidate Details

Structure:
CMap ID: C00117
Pert ID: BRD-A04352665
Compound Name: maraviroc
Targets: CCR5
MoA: CCK receptor antagonist
SMILES: CC(C)c1nnc(C)n1C1CC2CCC(C1)N2CC[C@H](NC(=O)C1CCC(F)(F)CC1)c1ccccc1
InchiKey: GSNHKUDZZFZSJB-ILVMPNSOSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
9262 BRD-A04352665 AGS 10 uM 6 h 0.29 1.19 0.42 0.25 0.89 0.2
10284 BRD-A04352665 HCC515 10 uM 6 h 0.0 0.0 0.0 -0.29 -0.97 0.45
10647 BRD-A04352665 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
11315 BRD-A04352665 NCIH2073 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
11886 BRD-A04352665 NCIH596 10 uM 6 h 0.0 0.0 0.0 -0.24 -0.8 0.12
12641 BRD-A04352665 SW480 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
13412 BRD-A04352665 VCAP 10 uM 24 h 0.0 0.0 0.0 0.33 1.17 0.97
122532 BRD-A04352665 A375 3.33 uM 24 h 0.21 0.89 0.02 0.25 0.9 0.22
122562 BRD-A04352665 A549 10 uM 24 h 0.0 0.0 0.0 -0.22 -0.72 0.04
122592 BRD-A04352665 HA1E 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122618 BRD-A04352665 HEK293 3.33 uM 24 h 0.27 1.12 0.26 0.42 1.48 2.24
122650 BRD-A04352665 HELA 3.33 uM 24 h -0.27 -1.11 0.37 0.31 1.09 0.67
122668 BRD-A04352665 HT29 10 uM 24 h 0.21 0.89 0.02 0.17 0.62 0.0
122697 BRD-A04352665 MCF10A 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131018 BRD-A04352665 HUVEC 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131071 BRD-A04352665 MCF??7.00 0.01 uM 24 h 0.21 0.87 0.01 -0.42 -1.4 2.02
131103 BRD-A04352665 MDAMB231 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131137 BRD-A04352665 PC3 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131167 BRD-A04352665 YAPC 0.74 uM 24 h 0.24 0.98 0.09 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).