CMap Candidate Details

Structure:
CMap ID: C01174
Pert ID: BRD-A48570745
Compound Name: ivermectin
Targets: --
MoA: --
SMILES: CCC(C)[C@H]1O[C@]2(CC[C@@H]1C)C[C@@H]1C[C@@H](CC=C(C)[C@@H](OC3C[C@H](OC)C(O[C@H]4C[C@H](OC)[C@@H](O)[C@H](C)O4)[C@H](C)O3)[C@@H](C)C=CC=C3/CO[C@@H]4[C@H](O)C(C)=C[C@@H](C(=O)O1)[C@]34O)O2
InchiKey: AZSNMRSAGSSBNP-ONDMGMIHSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
4308 BRD-A48570745 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
4997 BRD-A48570745 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
37240 BRD-A48570745 A549 10 uM 24 h 0.0 0.0 0.0 -0.42 -1.41 2.02
37508 BRD-A48570745 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
37827 BRD-A48570745 HEPG2 10 uM 6 h 0.0 0.0 0.0 -0.36 -1.2 1.22
38152 BRD-A48570745 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 -0.43 -1.46 15.35
125321 BRD-A48570745 HEK293 10 uM 24 h 0.27 1.11 0.26 0.0 0.0 0.0
125355 BRD-A48570745 HELA 3.33 uM 24 h 0.0 0.0 0.0 -0.37 -1.26 1.36
125377 BRD-A48570745 HT29 10 uM 24 h 0.0 0.0 0.0 -0.48 -1.62 15.65
125418 BRD-A48570745 MCF10A 1.11 uM 24 h -0.32 -1.35 0.98 0.0 0.0 0.0
125524 BRD-A48570745 THP1 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
125550 BRD-A48570745 YAPC 10 uM 24 h 0.18 0.77 0.0 -0.32 -1.06 0.75
133344 BRD-A48570745 A375 2.22 uM 24 h 0.33 1.37 0.97 -0.26 -0.89 0.27
133393 BRD-A48570745 HA1E 2.22 uM 24 h 0.0 0.0 0.0 -0.37 -1.25 1.35
133487 BRD-A48570745 JURKAT 0.01 uM 24 h 0.0 0.0 0.0 -0.32 -1.09 0.82
133559 BRD-A48570745 MDAMB231 0.08 uM 24 h 0.0 0.0 0.0 0.31 1.09 0.67
133585 BRD-A48570745 PC3 2.22 uM 24 h 0.29 1.23 0.49 -0.25 -0.86 0.21
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).