CMap Candidate Details

Structure:
CMap ID: C11750
Pert ID: BRD-K29530284
Compound Name: amlexanox
Targets: --
MoA: --
SMILES: CC(C)c1ccc2oc3nc(N)c(cc3c(=O)c2c1)C(O)=O
InchiKey: SGRYPYWGNKJSDL-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
25348 BRD-K29530284 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121891 BRD-K29530284 A375 10 uM 24 h 0.0 0.0 0.0 0.28 1.0 0.42
122043 BRD-K29530284 HUVEC 10 uM 24 h -0.23 -0.95 0.09 0.0 0.0 0.0
122089 BRD-K29530284 MCF10A 10 uM 24 h -0.25 -1.06 0.26 -0.31 -1.03 0.65
122137 BRD-K29530284 MDAMB231 10 uM 24 h 0.0 0.0 0.0 -0.33 -1.1 0.87
122188 BRD-K29530284 THP1 1.11 uM 24 h 0.19 0.8 0.0 0.32 1.13 0.82
130199 BRD-K29530284 A549 0.03 uM 24 h 0.0 0.0 0.0 -0.25 -0.83 0.17
130223 BRD-K29530284 HA1E 0.01 uM 24 h -0.2 -0.84 0.0 0.0 0.0 0.0
130255 BRD-K29530284 HEK293 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130285 BRD-K29530284 HELA 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130316 BRD-K29530284 HT29 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130344 BRD-K29530284 JURKAT 0.25 uM 24 h 0.0 0.0 0.0 -0.27 -0.91 0.3
130428 BRD-K29530284 MCF??7.00 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130477 BRD-K29530284 PC3 0.74 uM 24 h 0.0 0.0 0.0 -0.24 -0.8 0.12
130518 BRD-K29530284 YAPC 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).