CMap Candidate Details

Structure:
CMap ID: C01177
Pert ID: BRD-A48809242
Compound Name: IB-MECA
Targets: ADORA3
MoA: Adenosine receptor agonist
SMILES: CNC(=O)[C@H]1O[C@H](C(O)[C@H]1O)n2cnc3c(NCc4cccc(I)c4)ncnc23
InchiKey: HUJXGQILHAUCCV-FEWYLQRLSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
6652 BRD-A48809242 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
7081 BRD-A48809242 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
7396 BRD-A48809242 HA1E 10 uM 6 h -0.32 -1.33 0.87 0.0 0.0 0.0
7550 BRD-A48809242 HCC515 10 uM 6 h 0.0 0.0 0.0 0.22 0.79 0.08
7953 BRD-A48809242 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
8243 BRD-A48809242 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
8451 BRD-A48809242 PC3 10 uM 6 h -0.3 -1.26 0.72 -0.39 -1.3 1.6
8586 BRD-A48809242 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
100189 BRD-A48809242 U2OS 10 uM 6 h -0.34 -1.41 1.4 -0.35 -1.18 1.14
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).