CMap Candidate Details

Structure:
CMap ID: C11800
Pert ID: BRD-K29668683
Compound Name: BD-1063
Targets: SIGMAR1
MoA: Sigma receptor antagonist
SMILES: CN1CCN(CCc2ccc(Cl)c(Cl)c2)CC1
InchiKey: SUIZRDJCBVPASY-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1578 BRD-K29668683 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
1914 BRD-K29668683 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
2391 BRD-K29668683 PC3 10 uM 6 h -0.22 -0.9 0.04 -0.29 -0.97 0.44
2636 BRD-K29668683 VCAP 10 uM 24 h 0.0 0.0 0.0 -0.28 -0.93 0.36
41761 BRD-K29668683 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
41927 BRD-K29668683 A549 10 uM 24 h 0.23 0.97 0.08 0.0 0.0 0.0
42347 BRD-K29668683 ASC 10 uM 24 h 0.0 0.0 0.0 0.3 1.05 0.58
42673 BRD-K29668683 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
42978 BRD-K29668683 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43183 BRD-K29668683 MCF??7.00 10 uM 24 h -0.25 -1.06 0.24 -0.26 -0.88 0.25
43538 BRD-K29668683 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
43836 BRD-K29668683 PHH 10 uM 24 h 0.0 0.0 0.0 0.34 1.21 1.15
44106 BRD-K29668683 SKB 10 uM 24 h -0.33 -1.36 1.07 0.0 0.0 0.0
99813 BRD-K29668683 U2OS 10 uM 6 h -0.21 -0.89 0.03 0.18 0.62 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).