CMap Candidate Details

Structure:
CMap ID: C01181
Pert ID: BRD-A49046702
Compound Name: SKF-89976A
Targets: SLC6A1
MoA: GABA uptake inhibitor
SMILES: OC(=O)C1CCCN(CCC=C(c2ccccc2)c2ccccc2)C1
InchiKey: TXQKSMSLZVKQBI-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
2809 BRD-A49046702 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
3104 BRD-A49046702 HCC515 10 uM 24 h 0.0 0.0 0.0 -0.24 -0.8 0.12
3440 BRD-A49046702 PC3 10 uM 24 h 0.0 0.0 0.0 -0.49 -1.64 15.65
3687 BRD-A49046702 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
39046 BRD-A49046702 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39273 BRD-A49046702 A549 10 uM 24 h 0.0 0.0 0.0 -0.23 -0.78 0.1
39569 BRD-A49046702 ASC 10 uM 24 h 0.0 0.0 0.0 -0.26 -0.88 0.24
39895 BRD-A49046702 HEPG2 10 uM 6 h 0.22 0.92 0.04 0.26 0.9 0.23
40178 BRD-A49046702 HT29 10 uM 6 h 0.0 0.0 0.0 -0.29 -0.97 0.46
40426 BRD-A49046702 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
40697 BRD-A49046702 NEU 10 uM 24 h 0.0 0.0 0.0 0.36 1.28 1.37
40995 BRD-A49046702 NPC 10 uM 24 h 0.31 1.29 0.64 -0.29 -0.99 0.5
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).