CMap Candidate Details

Structure:
CMap ID: C11820
Pert ID: BRD-K29735307
Compound Name: ostarine
Targets: AR
MoA: Androgen receptor modulator
SMILES: C[C@](O)(COc1ccc(cc1)C#N)C(=O)Nc1ccc(C#N)c(c1)C(F)(F)F
InchiKey: JNGVJMBLXIUVRD-SFHVURJKSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
120004 BRD-K29735307 A549 1.11 uM 24 h 0.24 1.02 0.12 0.39 1.38 2.16
120064 BRD-K29735307 HELA 0.04 uM 24 h 0.25 1.05 0.16 0.33 1.17 0.92
120120 BRD-K29735307 HT29 0.37 uM 24 h 0.27 1.13 0.28 0.0 0.0 0.0
120162 BRD-K29735307 MCF??7.00 0.04 uM 24 h 0.23 0.97 0.08 0.0 0.0 0.0
120197 BRD-K29735307 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120222 BRD-K29735307 YAPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
128800 BRD-K29735307 A375 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
128821 BRD-K29735307 HA1E 2.22 uM 24 h 0.0 0.0 0.0 0.26 0.94 0.28
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).