CMap Candidate Details

Structure:
CMap ID: C01184
Pert ID: BRD-A49172652
Compound Name: lansoprazole
Targets: ATP4A
MoA: ATPase inhibitor
SMILES: Cc1c(OCC(F)(F)F)ccnc1CS(=O)c1nc2ccccc2[nH]1
InchiKey: MJIHNNLFOKEZEW-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
24388 BRD-A49172652 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
24534 BRD-A49172652 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
24727 BRD-A49172652 HA1E 10 uM 6 h 0.0 0.0 0.0 -0.33 -1.11 0.92
24847 BRD-A49172652 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
25130 BRD-A49172652 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
25298 BRD-A49172652 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
52020 BRD-A49172652 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
100190 BRD-A49172652 U2OS 10 uM 6 h 0.0 0.0 0.0 0.18 0.65 0.01
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).