CMap Candidate Details

Structure:
CMap ID: C01185
Pert ID: BRD-A49225603
Compound Name: alimemazine
Targets: HRH1
MoA: Histamine receptor ligand; Histamine receptor agonist
SMILES: CC(CN(C)C)CN1c2ccccc2Sc2ccccc12
InchiKey: ZZHLYYDVIOPZBE-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
6841 BRD-A49225603 A375 10 uM 6 h -0.29 -1.23 0.63 0.0 0.0 0.0
6937 BRD-A49225603 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
7234 BRD-A49225603 HA1E 10 uM 24 h -0.25 -1.02 0.19 0.38 1.35 1.72
7551 BRD-A49225603 HCC515 10 uM 6 h -0.2 -0.82 0.0 0.45 1.61 2.39
7775 BRD-A49225603 HT29 10 uM 24 h -0.2 -0.83 0.0 0.32 1.13 0.84
8049 BRD-A49225603 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 -0.31 -1.05 0.7
8307 BRD-A49225603 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
8762 BRD-A49225603 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).