CMap Candidate Details

Structure:
CMap ID: C01186
Pert ID: BRD-A49358627
Compound Name: ciprofibrate
Targets: PPARA
MoA: PPAR receptor agonist
SMILES: CC(C)(Oc1ccc(cc1)C1CC1(Cl)Cl)C(O)=O
InchiKey: KPSRODZRAIWAKH-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1694 BRD-A49358627 HA1E 10 uM 6 h 0.0 0.0 0.0 -0.25 -0.83 0.17
1829 BRD-A49358627 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
2281 BRD-A49358627 PC3 10 uM 24 h -0.24 -1.0 0.14 -0.3 -1.01 0.57
2763 BRD-A49358627 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
41672 BRD-A49358627 A375 10 uM 6 h -0.27 -1.12 0.38 0.0 0.0 0.0
42014 BRD-A49358627 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
42212 BRD-A49358627 ASC 10 uM 24 h -0.21 -0.87 0.02 -0.24 -0.8 0.12
42862 BRD-A49358627 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43413 BRD-A49358627 NPC 10 uM 24 h 0.0 0.0 0.0 0.34 1.2 1.13
43723 BRD-A49358627 PHH 10 uM 24 h 0.0 0.0 0.0 -0.36 -1.2 1.22
52095 BRD-A49358627 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
52947 BRD-A49358627 HEPG2 20 uM 3 h -0.24 -0.99 0.13 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).