CMap Candidate Details

Structure:
CMap ID: C01187
Pert ID: BRD-A49370193
Compound Name: Ro-60-0175
Targets: HTR2A; HTR2B; HTR2C
MoA: Serotonin receptor agonist
SMILES: CC(N)Cn1ccc2cc(F)c(Cl)cc12
InchiKey: XJJZQXUGLLXTHO-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1500 BRD-A49370193 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
1830 BRD-A49370193 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
2269 BRD-A49370193 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
39047 BRD-A49370193 A375 10 uM 6 h 0.0 0.0 0.0 -0.27 -0.91 0.31
39397 BRD-A49370193 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39570 BRD-A49370193 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
39896 BRD-A49370193 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40179 BRD-A49370193 HT29 10 uM 6 h -0.21 -0.88 0.03 0.0 0.0 0.0
40568 BRD-A49370193 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.27 0.96 0.33
40698 BRD-A49370193 NEU 10 uM 24 h 0.0 0.0 0.0 -0.34 -1.16 1.1
40996 BRD-A49370193 NPC 10 uM 24 h -0.28 -1.15 0.43 -0.27 -0.9 0.29
41319 BRD-A49370193 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
90282 BRD-A49370193 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
100191 BRD-A49370193 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).