CMap Candidate Details
Structure:
CMap ID: | C11871 |
Pert ID: | BRD-K29950728 |
Compound Name: | clomifene |
Targets: | ESR1 |
MoA: | Estrogen receptor antagonist |
SMILES: | CCN(CC)CCOc1ccc(cc1)C(=C(/Cl)c1ccccc1)c1ccccc1 |
InchiKey: | GKIRPKYJQBWNGO-QPLCGJKRSA-N |
Compound Aliases: | -- |
Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
---|---|---|---|---|---|---|---|---|---|---|
5605 | BRD-K29950728 | HCC515 | 10 uM | 24 h | 0.22 | 0.92 | 0.04 | 0.33 | 1.19 | 1.01 |
42348 | BRD-K29950728 | ASC | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
42674 | BRD-K29950728 | HEPG2 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.28 | 0.99 | 0.41 |
43539 | BRD-K29950728 | NPC | 10 uM | 24 h | -0.2 | -0.82 | 0.0 | -0.36 | -1.2 | 1.2 |
43837 | BRD-K29950728 | PHH | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
44107 | BRD-K29950728 | SKB | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.24 | 0.87 | 0.17 |
51139 | BRD-K29950728 | VCAP | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
95335 | BRD-K29950728 | A549 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
95462 | BRD-K29950728 | U2OS | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
121893 | BRD-K29950728 | A375 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
121935 | BRD-K29950728 | HA1E | 10 uM | 24 h | 0.26 | 1.08 | 0.21 | 0.44 | 1.57 | 2.34 |
121955 | BRD-K29950728 | HEK293 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
121980 | BRD-K29950728 | HELA | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
122007 | BRD-K29950728 | HT29 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
122045 | BRD-K29950728 | HUVEC | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
122139 | BRD-K29950728 | MDAMB231 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.34 | 1.21 | 1.13 |
122163 | BRD-K29950728 | PC3 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
122190 | BRD-K29950728 | THP1 | 0.04 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
122218 | BRD-K29950728 | YAPC | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
130346 | BRD-K29950728 | JURKAT | 0.03 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
130395 | BRD-K29950728 | MCF10A | 2.22 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.23 | -0.79 | 0.11 |
130430 | BRD-K29950728 | MCF??7.00 | 2.22 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |