CMap Candidate Details

Structure:
CMap ID: C11877
Pert ID: BRD-K29968218
Compound Name: KX-2391
Targets: --
MoA: --
SMILES: O=C(Cc1ccc(cn1)-c1ccc(OCCN2CCOCC2)cc1)NCc1ccccc1
InchiKey: HUNGUWOZPQBXGX-UHFFFAOYSA-N
Compound Aliases: KX-2-391

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
122048 BRD-K29968218 HUVEC 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122106 BRD-K29968218 MCF??7.00 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122165 BRD-K29968218 PC3 1.11 uM 24 h -0.23 -0.96 0.1 -0.35 -1.18 1.14
122192 BRD-K29968218 THP1 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130184 BRD-K29968218 A375 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130203 BRD-K29968218 A549 0.74 uM 24 h -0.22 -0.91 0.05 0.0 0.0 0.0
130227 BRD-K29968218 HA1E 2.22 uM 24 h -0.21 -0.88 0.03 -0.32 -1.06 0.74
130257 BRD-K29968218 HEK293 2.22 uM 24 h 0.0 0.0 0.0 -0.35 -1.17 1.13
130289 BRD-K29968218 HELA 0.25 uM 24 h -0.23 -0.96 0.09 -0.38 -1.28 1.45
130317 BRD-K29968218 HT29 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130349 BRD-K29968218 JURKAT 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130398 BRD-K29968218 MCF10A 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130449 BRD-K29968218 MDAMB231 2.22 uM 24 h 0.0 0.0 0.0 -0.23 -0.76 0.07
130520 BRD-K29968218 YAPC 0.01 uM 24 h -0.17 -0.71 0.0 0.23 0.82 0.1
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).