CMap Candidate Details

Structure:
CMap ID: C01188
Pert ID: BRD-A49399758
Compound Name: desmopressin-acetate
Targets: AVPR1A; AVPR1B; AVPR2
MoA: Vasopressin receptor agonist
SMILES: NC(=O)CCC1NC(=O)C(Cc2ccccc2)NC(=O)C(Cc2ccc(O)cc2)NC(=O)CCSSCC(NC(=O)C(CC(N)=O)NC1=O)C(=O)N1CCCC1C(=O)NC(CCCNC(N)=N)C(=O)NCC(N)=O
InchiKey: NFLWUMRGJYTJIN-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
125264 BRD-A49399758 A549 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
125328 BRD-A49399758 HEK293 10 uM 24 h 0.0 0.0 0.0 -0.22 -0.72 0.04
125420 BRD-A49399758 MCF10A 3.33 uM 24 h -0.21 -0.89 0.04 -0.26 -0.88 0.24
125455 BRD-A49399758 MCF??7.00 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
125499 BRD-A49399758 PC3 0.37 uM 24 h 0.0 0.0 0.0 -0.3 -1.01 0.57
125528 BRD-A49399758 THP1 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133347 BRD-A49399758 A375 0.01 uM 24 h 0.0 0.0 0.0 -0.3 -1.01 0.57
133396 BRD-A49399758 HA1E 0.74 uM 24 h 0.0 0.0 0.0 0.26 0.91 0.23
133431 BRD-A49399758 HELA 0.01 uM 24 h -0.29 -1.2 0.55 0.0 0.0 0.0
133461 BRD-A49399758 HT29 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133488 BRD-A49399758 JURKAT 0.01 uM 24 h -0.22 -0.93 0.07 0.22 0.77 0.06
133563 BRD-A49399758 MDAMB231 0.74 uM 24 h 0.23 0.97 0.08 -0.34 -1.13 0.98
133641 BRD-A49399758 YAPC 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).