CMap Candidate Details

Structure:
CMap ID: C11901
Pert ID: BRD-K30064966
Compound Name: BRD-K30064966
Targets: CASP3
MoA: Caspase activator
SMILES: Oc1cccc2cc(C(=O)Nc3cccc(c3)-c3cn4ccccc4n3)c(=O)oc12
InchiKey: FCODPGUEFHCCIA-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
9195 BRD-K30064966 A549 12 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
9402 BRD-K30064966 AGS 12 uM 6 h 0.0 0.0 0.0 -0.22 -0.73 0.05
10497 BRD-K30064966 HCT116 12 uM 6 h 0.2 0.82 0.0 0.0 0.0 0.0
11464 BRD-K30064966 NCIH2073 12 uM 6 h 0.25 1.04 0.15 0.0 0.0 0.0
11745 BRD-K30064966 NCIH508 12 uM 6 h 0.23 0.95 0.06 -0.22 -0.74 0.05
12298 BRD-K30064966 NOMO1 12 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12569 BRD-K30064966 PC3 12 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
12773 BRD-K30064966 SW480 12 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
13114 BRD-K30064966 THP1 12 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
13252 BRD-K30064966 U937 12 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
13608 BRD-K30064966 VCAP 12 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
118061 BRD-K30064966 A375 0.37 uM 24 h 0.18 0.75 0.0 -0.25 -0.85 0.19
118147 BRD-K30064966 HA1E 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
118193 BRD-K30064966 HCC515 1.25 uM 24 h 0.0 0.0 0.0 -0.29 -0.97 0.45
118243 BRD-K30064966 HEPG2 0.05 uM 24 h 0.0 0.0 0.0 -0.33 -1.1 0.86
118285 BRD-K30064966 HT29 1.25 uM 24 h 0.21 0.87 0.01 -0.33 -1.12 0.95
118325 BRD-K30064966 MCF??7.00 12 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).