CMap Candidate Details

Structure:
CMap ID: C01193
Pert ID: BRD-A49680073
Compound Name: BRD-A49680073
Targets: --
MoA: --
SMILES: CC(C)(O)/C=C/C(=O)[C@](C)(O)C1[C@H](O)C[C@@]2(C)[C@@H]3CC=C4C(CC(=O)C(=O)C4(C)C)[C@]3(C)C(=O)C[C@@]12C
InchiKey: NZZOMHODWAPPJH-YPXOEWKESA-N
Compound Aliases: cucurbitacin-i

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1695 BRD-A49680073 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
2041 BRD-A49680073 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
2339 BRD-A49680073 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
2750 BRD-A49680073 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39048 BRD-A49680073 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39398 BRD-A49680073 A549 10 uM 6 h -0.3 -1.25 0.68 -0.44 -1.47 15.35
39571 BRD-A49680073 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
39897 BRD-A49680073 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40180 BRD-A49680073 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40427 BRD-A49680073 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 -0.36 -1.22 1.25
40699 BRD-A49680073 NEU 10 uM 24 h 0.31 1.3 0.69 0.0 0.0 0.0
40997 BRD-A49680073 NPC 10 uM 24 h 0.0 0.0 0.0 -0.35 -1.17 1.11
41320 BRD-A49680073 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
53549 BRD-A49680073 HUH7 2.5 uM 6 h -0.27 -1.14 0.42 0.0 0.0 0.0
53632 BRD-A49680073 PHH 2.5 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
100193 BRD-A49680073 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).