CMap Candidate Details

Structure:
CMap ID: C11937
Pert ID: BRD-K30197592
Compound Name: 5-methoxytryptamine
Targets: HTR2A; HTR6
MoA: Serotonin receptor agonist
SMILES: COc1ccc2[nH]cc(CCN)c2c1
InchiKey: JTEJPPKMYBDEMY-UHFFFAOYSA-N
Compound Aliases: 5-METHOXYTRYPTAMINE

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
22467 BRD-K30197592 HA1E 10 uM 6 h 0.0 0.0 0.0 -0.32 -1.06 0.75
22739 BRD-K30197592 HCC515 10 uM 6 h 0.0 0.0 0.0 0.22 0.77 0.06
23026 BRD-K30197592 HEPG2 10 uM 6 h 0.23 0.97 0.08 0.0 0.0 0.0
23839 BRD-K30197592 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
24299 BRD-K30197592 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
44356 BRD-K30197592 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
44690 BRD-K30197592 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
44915 BRD-K30197592 ASC 10 uM 24 h 0.0 0.0 0.0 -0.34 -1.14 1.01
45485 BRD-K30197592 HT29 10 uM 6 h -0.17 -0.7 0.0 0.0 0.0 0.0
45800 BRD-K30197592 MCF??7.00 10 uM 6 h 0.32 1.34 0.88 0.0 0.0 0.0
46033 BRD-K30197592 NPC 10 uM 24 h -0.22 -0.92 0.06 -0.32 -1.07 0.75
46350 BRD-K30197592 PHH 10 uM 24 h 0.19 0.81 0.0 0.25 0.87 0.17
46668 BRD-K30197592 SKB 10 uM 24 h 0.0 0.0 0.0 0.27 0.94 0.29
99815 BRD-K30197592 U2OS 10 uM 6 h 0.31 1.29 0.64 -0.26 -0.86 0.22
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).