CMap Candidate Details

Structure:
CMap ID: C11957
Pert ID: BRD-K30240666
Compound Name: clemastine
Targets: HRH1
MoA: Histamine receptor antagonist
SMILES: CN1CCC[C@@H]1CCO[C@](C)(c1ccccc1)c1ccc(Cl)cc1
InchiKey: YNNUSGIPVFPVBX-NHCUHLMSSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5198 BRD-K30240666 A375 10 uM 6 h 0.0 0.0 0.0 0.22 0.78 0.07
5313 BRD-K30240666 HA1E 10 uM 24 h -0.22 -0.92 0.07 0.0 0.0 0.0
5607 BRD-K30240666 HCC515 10 uM 24 h 0.0 0.0 0.0 0.28 0.99 0.39
6269 BRD-K30240666 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
6535 BRD-K30240666 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
41928 BRD-K30240666 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
42350 BRD-K30240666 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
42676 BRD-K30240666 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.38 1.35 1.72
42980 BRD-K30240666 HT29 10 uM 6 h 0.0 0.0 0.0 0.35 1.25 1.28
43184 BRD-K30240666 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
43541 BRD-K30240666 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
43839 BRD-K30240666 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
91063 BRD-K30240666 HUH7 10 uM 72 h 0.0 0.0 0.0 0.0 0.0 0.0
99817 BRD-K30240666 U2OS 4 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).