CMap Candidate Details

Structure:
CMap ID: C01196
Pert ID: BRD-A49838158
Compound Name: phenprocoumon
Targets: VKORC1
MoA: Vitamin K antagonist
SMILES: CCC(c1ccccc1)c1c(O)c2ccccc2oc1=O
InchiKey: DQDAYGNAKTZFIW-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
121727 BRD-A49838158 A375 0.37 uM 24 h 0.0 0.0 0.0 0.29 1.04 0.56
121748 BRD-A49838158 HA1E 0.37 uM 24 h -0.27 -1.14 0.43 -0.29 -0.98 0.47
121779 BRD-A49838158 HELA 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121811 BRD-A49838158 HT29 3.33 uM 24 h 0.25 1.04 0.14 -0.25 -0.85 0.2
121879 BRD-A49838158 YAPC 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129855 BRD-A49838158 HEK293 0.08 uM 24 h 0.0 0.0 0.0 -0.26 -0.87 0.23
129930 BRD-A49838158 JURKAT 0.03 uM 24 h 0.0 0.0 0.0 0.32 1.12 0.79
129980 BRD-A49838158 MCF10A 0.25 uM 24 h 0.17 0.72 0.0 0.3 1.08 0.65
130014 BRD-A49838158 MCF??7.00 0.25 uM 24 h -0.2 -0.83 0.0 -0.36 -1.2 1.2
130066 BRD-A49838158 MDAMB231 0.25 uM 24 h -0.27 -1.11 0.38 0.0 0.0 0.0
130090 BRD-A49838158 PC3 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130137 BRD-A49838158 THP1 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).