CMap Candidate Details

Structure:
CMap ID: C11972
Pert ID: BRD-K30296925
Compound Name: flavokavain-b
Targets: IKBKB
MoA: Anti-cancer agent
SMILES: COc1cc(O)c(C(=O)/C=C/c2ccccc2)c(OC)c1
InchiKey: QKQLSQLKXBHUSO-CMDGGOBGSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
4092 BRD-K30296925 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
4408 BRD-K30296925 HCC515 10 uM 24 h 0.0 0.0 0.0 0.24 0.83 0.12
4672 BRD-K30296925 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
5066 BRD-K30296925 VCAP 10 uM 6 h 0.0 0.0 0.0 -0.24 -0.8 0.11
37140 BRD-K30296925 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
37278 BRD-K30296925 A549 10 uM 24 h -0.27 -1.12 0.39 0.0 0.0 0.0
37632 BRD-K30296925 ASC 10 uM 24 h 0.0 0.0 0.0 0.25 0.87 0.17
37892 BRD-K30296925 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
38071 BRD-K30296925 HT29 10 uM 6 h 0.0 0.0 0.0 0.37 1.33 1.72
38194 BRD-K30296925 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.24 0.86 0.16
38459 BRD-K30296925 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
38708 BRD-K30296925 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
38939 BRD-K30296925 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).