CMap Candidate Details

Structure:
CMap ID: C11989
Pert ID: BRD-K30351863
Compound Name: BRD-K30351863
Targets: APEX1
MoA: APEX inhibitor
SMILES: CC(=O)Nc1sc2CNCc2c1-c1nc2ccccc2s1
InchiKey: MODNMLYGANOZDZ-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
16451 BRD-K30351863 A375 10 uM 6 h -0.26 -1.07 0.28 -0.35 -1.17 1.11
16636 BRD-K30351863 A549 10 uM 6 h -0.24 -0.99 0.13 -0.26 -0.86 0.21
16967 BRD-K30351863 HCC515 10 uM 6 h 0.0 0.0 0.0 0.25 0.87 0.17
17296 BRD-K30351863 HEPG2 10 uM 6 h 0.19 0.81 0.0 0.0 0.0 0.0
17638 BRD-K30351863 HT29 10 uM 6 h 0.0 0.0 0.0 0.23 0.8 0.08
17947 BRD-K30351863 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
18258 BRD-K30351863 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
18577 BRD-K30351863 VCAP 10 uM 24 h 0.27 1.11 0.25 -0.29 -0.96 0.44
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).