CMap Candidate Details

Structure:
CMap ID: C01200
Pert ID: BRD-A50033377
Compound Name: rivaroxaban
Targets: F10
MoA: Coagulation factor inhibitor
SMILES: Clc1ccc(s1)C(=O)NCC1CN(C(=O)O1)c1ccc(cc1)N1CCOCC1=O
InchiKey: KGFYHTZWPPHNLQ-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
96605 BRD-A50033377 A375 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
125759 BRD-A50033377 HUVEC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
125790 BRD-A50033377 JURKAT 3.33 uM 24 h -0.34 -1.4 1.16 0.0 0.0 0.0
125811 BRD-A50033377 MCF10A 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
125838 BRD-A50033377 MCF??7.00 0.04 uM 24 h -0.18 -0.74 0.0 -0.2 -0.69 0.02
125859 BRD-A50033377 MDAMB231 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
125957 BRD-A50033377 YAPC 10 uM 24 h -0.34 -1.41 1.42 0.0 0.0 0.0
133679 BRD-A50033377 A549 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133718 BRD-A50033377 HA1E 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133747 BRD-A50033377 HEK293 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133779 BRD-A50033377 HELA 0.25 uM 24 h 0.25 1.06 0.19 0.0 0.0 0.0
133812 BRD-A50033377 HT29 0.03 uM 24 h 0.0 0.0 0.0 0.22 0.79 0.07
133959 BRD-A50033377 PC3 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
133993 BRD-A50033377 THP1 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).