CMap Candidate Details

Structure:
CMap ID: C12026
Pert ID: BRD-K30466858
Compound Name: ellagic-acid
Targets: CA14; SYK; CA2; CA4; CA6; CA9; CA12
MoA: HCV inhibitor; HIV integrase inhibitor; Beta-secretase inhibitor; Aldose reductase inhibitor; Reverse transcriptase inhibitor; Glutathione transferase inhibitor; Quorum sensing signaling modulator
SMILES: Oc1cc2c3c(oc(=O)c4cc(O)c(O)c(oc2=O)c34)c1O
InchiKey: AFSDNFLWKVMVRB-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
90631 BRD-K30466858 HCT116 10 uM 24 h 0.0 0.0 0.0 -0.25 -0.84 0.18
90664 BRD-K30466858 MCF10A 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
96438 BRD-K30466858 A375 10 uM 24 h 0.0 0.0 0.0 -0.28 -0.95 0.42
96505 BRD-K30466858 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
98022 BRD-K30466858 MCF??7.00 0.37 uM 24 h 0.23 0.96 0.08 0.0 0.0 0.0
98069 BRD-K30466858 P1A82 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
98750 BRD-K30466858 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
98882 BRD-K30466858 NEU 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120009 BRD-K30466858 A549 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120038 BRD-K30466858 HA1E 0.125 uM 24 h 0.0 0.0 0.0 0.4 1.43 2.2
120076 BRD-K30466858 HELA 3.33 uM 3 h 0.0 0.0 0.0 0.0 0.0 0.0
120124 BRD-K30466858 HT29 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120226 BRD-K30466858 YAPC 1.11 uM 24 h -0.2 -0.85 0.01 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).