CMap Candidate Details
Structure:
| CMap ID: | C01203 |
| Pert ID: | BRD-A50287119 |
| Compound Name: | sirolimus |
| Targets: | FKBP1A; MTOR |
| MoA: | MTOR inhibitor |
| SMILES: | CO[C@@H]1C[C@H](CC(C)[C@@H]2CC(=O)[C@H](C)C=C(C)[C@@H](O)[C@@H](OC)C(=O)[C@H](C)C[C@H](C)C=CC=CC=C(C)[C@H](C[C@@H]3CC[C@@H](C)[C@@](O)(O3)C(=O)C(=O)N3CCCC[C@H]3C(=O)O2)OC)CC[C@H]1O |
| InchiKey: | QFJCIRLUMZQUOT-DENUVPQMSA-N |
| Compound Aliases: | -- |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 98841 | BRD-A50287119 | NEU | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 99117 | BRD-A50287119 | NPC | 10 uM | 24 h | 0.24 | 1.0 | 0.11 | -0.28 | -0.93 | 0.35 |