CMap Candidate Details

Structure:
CMap ID: C12032
Pert ID: BRD-K30480208
Compound Name: torasemide
Targets: SLC12A1
MoA: Thromboxane receptor antagonist; Electrolyte reabsorption inhibitor
SMILES: CC(C)NC(=O)NS(=O)(=O)c1cnccc1Nc1cccc(C)c1
InchiKey: NGBFQHCMQULJNZ-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
7436 BRD-K30480208 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
7991 BRD-K30480208 HT29 10 uM 6 h 0.0 0.0 0.0 -0.26 -0.87 0.22
24663 BRD-K30480208 A549 10 uM 6 h 0.0 0.0 0.0 0.24 0.87 0.16
25350 BRD-K30480208 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120074 BRD-K30480208 HELA 0.04 uM 3 h 0.0 0.0 0.0 0.0 0.0 0.0
120164 BRD-K30480208 MCF??7.00 0.04 uM 24 h 0.33 1.38 0.97 -0.32 -1.08 0.79
120200 BRD-K30480208 PC3 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
128801 BRD-K30480208 A375 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
128885 BRD-K30480208 YAPC 0.03 uM 24 h 0.25 1.03 0.14 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).