CMap Candidate Details

Structure:
CMap ID: C12056
Pert ID: BRD-K30563334
Compound Name: rifabutin
Targets: --
MoA: --
SMILES: CO[C@H]1C=CO[C@@]2(C)Oc3c(C2=O)c2c(c(O)c3C)c(O)c(NC(=O)C(C)=CC=C[C@H](C)[C@H](O)[C@@H](C)[C@@H](O)[C@@H](C)[C@H](OC(C)=O)[C@@H]1C)c1=NC3(CCN(CC(C)C)CC3)N=c21
InchiKey: AZFBLLCNOQPJGJ-DVAZEERGSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
25351 BRD-K30563334 VCAP 10 uM 24 h -0.3 -1.27 0.74 -0.33 -1.11 0.9
121916 BRD-K30563334 A549 10 uM 24 h -0.19 -0.79 0.0 0.0 0.0 0.0
121957 BRD-K30563334 HEK293 0.125 uM 24 h 0.0 0.0 0.0 -0.24 -0.81 0.12
121981 BRD-K30563334 HELA 0.37 uM 24 h 0.0 0.0 0.0 0.2 0.71 0.02
122010 BRD-K30563334 HT29 10 uM 24 h 0.0 0.0 0.0 0.21 0.76 0.05
122049 BRD-K30563334 HUVEC 1.11 uM 24 h 0.0 0.0 0.0 0.33 1.19 1.01
122107 BRD-K30563334 MCF??7.00 3.33 uM 24 h 0.27 1.13 0.29 0.0 0.0 0.0
122141 BRD-K30563334 MDAMB231 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122166 BRD-K30563334 PC3 1.11 uM 24 h 0.0 0.0 0.0 0.2 0.72 0.02
130185 BRD-K30563334 A375 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130228 BRD-K30563334 HA1E 0.08 uM 24 h 0.0 0.0 0.0 -0.23 -0.76 0.07
130350 BRD-K30563334 JURKAT 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130399 BRD-K30563334 MCF10A 0.74 uM 24 h -0.3 -1.26 0.72 0.0 0.0 0.0
130495 BRD-K30563334 THP1 0.03 uM 24 h -0.23 -0.94 0.08 0.22 0.8 0.08
130521 BRD-K30563334 YAPC 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).