CMap Candidate Details

Structure:
CMap ID: C12060
Pert ID: BRD-K30570479
Compound Name: VU-0400195-3
Targets: GRM4
MoA: Glutamate receptor modulator
SMILES: Clc1cc(NC(=O)c2ccccn2)ccc1N1C(=O)[C@H]2[C@@H]3C[C@@H](C=C3)[C@H]2C1=O
InchiKey: LJUABYFUJVRUSJ-FRVJLOGJSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
19006 BRD-K30570479 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
19272 BRD-K30570479 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
19654 BRD-K30570479 HA1E 10 uM 6 h 0.31 1.29 0.64 -0.29 -0.96 0.44
19979 BRD-K30570479 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
20311 BRD-K30570479 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
20634 BRD-K30570479 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
20885 BRD-K30570479 MCF??7.00 10 uM 24 h 0.25 1.06 0.19 0.0 0.0 0.0
21422 BRD-K30570479 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
21731 BRD-K30570479 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).