CMap Candidate Details

Structure:
CMap ID: C01207
Pert ID: BRD-A50364343
Compound Name: veliparib
Targets: PARP2; PARP1
MoA: PARP inhibitor
SMILES: CC1(CCCN1)c1nc2c(cccc2[nH]1)C(N)=O
InchiKey: JNAHVYVRKWKWKQ-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
91788 BRD-A50364343 HS578T 0.08 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
91836 BRD-A50364343 MCF10A 10 uM 24 h 0.0 0.0 0.0 -0.21 -0.71 0.03
91865 BRD-A50364343 MCF??7.00 2.22 uM 24 h -0.32 -1.32 0.82 0.32 1.12 0.76
91886 BRD-A50364343 MDAMB231 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
91952 BRD-A50364343 SKBR3 2.22 uM 6 h 0.0 0.0 0.0 -0.21 -0.72 0.04
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).