CMap Candidate Details

Structure:
CMap ID: C12094
Pert ID: BRD-K30649484
Compound Name: mafenide
Targets: CA6
MoA: Carbonic anhydrase inhibitor
SMILES: NCc1ccc(cc1)S(N)(=O)=O
InchiKey: TYMRLRRVMHJFTF-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
19007 BRD-K30649484 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
19440 BRD-K30649484 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
19655 BRD-K30649484 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
19980 BRD-K30649484 HCC515 10 uM 6 h 0.0 0.0 0.0 -0.22 -0.74 0.05
20312 BRD-K30649484 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
20635 BRD-K30649484 HT29 10 uM 6 h 0.2 0.82 0.0 0.0 0.0 0.0
20886 BRD-K30649484 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
21451 BRD-K30649484 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
21732 BRD-K30649484 VCAP 10 uM 6 h 0.23 0.95 0.07 -0.37 -1.23 1.28
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).