CMap Candidate Details

Structure:
CMap ID: C12103
Pert ID: BRD-K30677119
Compound Name: PP-30
Targets: RAF1
MoA: RAF inhibitor
SMILES: CC(C)n1nc(-c2cccc(c2)C(=O)NC2=NCCC2)c2c(N)ncnc12
InchiKey: RWRBSEISHUTNQL-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
8930 BRD-K30677119 A375 12 uM 24 h 0.24 0.99 0.1 -0.27 -0.92 0.34
9095 BRD-K30677119 A549 12 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
9403 BRD-K30677119 AGS 12 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
9712 BRD-K30677119 H1299 12 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10052 BRD-K30677119 HA1E 12 uM 6 h -0.27 -1.13 0.41 0.0 0.0 0.0
10370 BRD-K30677119 HCC515 12 uM 6 h -0.3 -1.25 0.69 0.0 0.0 0.0
10498 BRD-K30677119 HCT116 12 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10770 BRD-K30677119 HEPG2 12 uM 6 h 0.0 0.0 0.0 -0.24 -0.8 0.11
11120 BRD-K30677119 HT29 12 uM 6 h 0.0 0.0 0.0 0.29 1.04 0.56
11242 BRD-K30677119 MCF??7.00 12 uM 24 h -0.17 -0.71 0.0 0.0 0.0 0.0
11465 BRD-K30677119 NCIH2073 12 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
11746 BRD-K30677119 NCIH508 12 uM 6 h -0.22 -0.91 0.05 -0.27 -0.91 0.3
12028 BRD-K30677119 NCIH596 12 uM 6 h -0.23 -0.97 0.11 0.23 0.82 0.1
12299 BRD-K30677119 NOMO1 12 uM 6 h 0.0 0.0 0.0 0.22 0.78 0.07
12603 BRD-K30677119 PC3 12 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12774 BRD-K30677119 SW480 12 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
13115 BRD-K30677119 THP1 12 uM 6 h 0.23 0.95 0.06 0.29 1.01 0.45
13253 BRD-K30677119 U937 12 uM 6 h -0.18 -0.76 0.0 0.0 0.0 0.0
13609 BRD-K30677119 VCAP 12 uM 6 h -0.21 -0.88 0.03 0.0 0.0 0.0
96044 BRD-K30677119 PHH 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).