CMap Candidate Details

Structure:
CMap ID: C12128
Pert ID: BRD-K30743633
Compound Name: TCPOBOP
Targets: NR1I3
MoA: CAR agonist
SMILES: Clc1cnc(Oc2ccc(Oc3ncc(Cl)cc3Cl)cc2)c(Cl)c1
InchiKey: BAFKRPOFIYPKBQ-UHFFFAOYSA-N
Compound Aliases: tcpobop

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
33641 BRD-K30743633 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
33898 BRD-K30743633 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
34077 BRD-K30743633 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
34342 BRD-K30743633 HA1E 10 uM 6 h 0.19 0.78 0.0 0.0 0.0 0.0
34592 BRD-K30743633 HCC515 10 uM 6 h 0.0 0.0 0.0 -0.23 -0.78 0.09
34862 BRD-K30743633 HEPG2 10 uM 6 h 0.16 0.67 0.0 0.0 0.0 0.0
35123 BRD-K30743633 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
35434 BRD-K30743633 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.28 0.98 0.38
35555 BRD-K30743633 NEU 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
35761 BRD-K30743633 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
36072 BRD-K30743633 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
36239 BRD-K30743633 PHH 10 uM 24 h 0.29 1.2 0.43 -0.23 -0.78 0.09
36532 BRD-K30743633 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
36802 BRD-K30743633 VCAP 10 uM 24 h 0.0 0.0 0.0 0.29 1.02 0.49
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).