CMap Candidate Details

Structure:
CMap ID: C12153
Pert ID: BRD-K30816563
Compound Name: ranitidine
Targets: HRH2
MoA: Histamine receptor antagonist
SMILES: CNC(=C[N+](=O)[O-])NCCSCc1ccc(CN(C)C)o1
InchiKey: VMXUWOKSQNHOCA-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5199 BRD-K30816563 A375 10 uM 6 h -0.26 -1.07 0.27 0.0 0.0 0.0
5314 BRD-K30816563 HA1E 10 uM 24 h -0.19 -0.79 0.0 0.0 0.0 0.0
5608 BRD-K30816563 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
5898 BRD-K30816563 HEPG2 10 uM 6 h 0.25 1.04 0.14 0.0 0.0 0.0
6014 BRD-K30816563 HT29 10 uM 6 h 0.23 0.98 0.09 -0.22 -0.74 0.05
6536 BRD-K30816563 VCAP 10 uM 6 h 0.0 0.0 0.0 -0.42 -1.41 2.02
44558 BRD-K30816563 A549 10 uM 24 h -0.29 -1.23 0.63 0.0 0.0 0.0
44916 BRD-K30816563 ASC 10 uM 24 h 0.0 0.0 0.0 -0.29 -0.97 0.45
45677 BRD-K30816563 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
46034 BRD-K30816563 NPC 10 uM 24 h 0.0 0.0 0.0 0.22 0.79 0.08
46351 BRD-K30816563 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
46669 BRD-K30816563 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
51453 BRD-K30816563 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).