CMap Candidate Details

Structure:
CMap ID: C12257
Pert ID: BRD-K31135544
Compound Name: IB-MECA
Targets: ADORA3
MoA: Adenosine receptor agonist
SMILES: CNC(=O)[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(NCc3cccc(I)c3)ncnc12
InchiKey: HUJXGQILHAUCCV-MOROJQBDSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
120509 BRD-K31135544 A375 10 uM 24 h 0.28 1.18 0.38 0.0 0.0 0.0
120542 BRD-K31135544 A549 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120588 BRD-K31135544 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120614 BRD-K31135544 HELA 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120643 BRD-K31135544 HT29 10 uM 24 h 0.0 0.0 0.0 0.22 0.77 0.06
120693 BRD-K31135544 JURKAT 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120746 BRD-K31135544 MCF??7.00 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120767 BRD-K31135544 PC3 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120799 BRD-K31135544 YAPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).