CMap Candidate Details

Structure:
CMap ID: C12287
Pert ID: BRD-K31238592
Compound Name: devazepide
Targets: CCKAR
MoA: CCK receptor antagonist
SMILES: CN1C(=O)[C@@H](NC(=O)c2cc3ccccc3[nH]2)N=C(c4ccccc4)c5ccccc15
InchiKey: NFHRQQKPEBFUJK-HSZRJFAPSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
4213 BRD-K31238592 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
4410 BRD-K31238592 HCC515 10 uM 24 h 0.0 0.0 0.0 0.3 1.06 0.61
4673 BRD-K31238592 PC3 10 uM 24 h 0.26 1.1 0.24 0.0 0.0 0.0
5068 BRD-K31238592 VCAP 10 uM 6 h 0.25 1.03 0.13 0.26 0.92 0.25
39115 BRD-K31238592 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39439 BRD-K31238592 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39666 BRD-K31238592 ASC 10 uM 24 h 0.0 0.0 0.0 0.28 1.0 0.42
39979 BRD-K31238592 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40255 BRD-K31238592 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40460 BRD-K31238592 MCF??7.00 10 uM 24 h -0.26 -1.1 0.35 -0.22 -0.75 0.07
40786 BRD-K31238592 NEU 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41087 BRD-K31238592 NPC 10 uM 24 h 0.19 0.8 0.0 -0.38 -1.26 1.39
41420 BRD-K31238592 SKB 10 uM 24 h 0.25 1.06 0.19 0.24 0.85 0.14
99823 BRD-K31238592 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).