CMap Candidate Details

Structure:
CMap ID: C01229
Pert ID: BRD-A51382177
Compound Name: fosinopril
Targets: ACE
MoA: Angiotensin converting enzyme inhibitor
SMILES: CCC(=O)O[C@@H](OP(=O)(CCCCc1ccccc1)CC(=O)N1C[C@@H](C[C@H]1C(O)=O)C1CCCCC1)C(C)C
InchiKey: BIDNLKIUORFRQP-AJTMIRJTSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
49949 BRD-A51382177 A549 10 uM 6 h -0.25 -1.02 0.19 0.0 0.0 0.0
51100 BRD-A51382177 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
121560 BRD-A51382177 A375 10 uM 24 h 0.0 0.0 0.0 -0.27 -0.89 0.27
121599 BRD-A51382177 HA1E 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121637 BRD-A51382177 HELA 0.125 uM 24 h -0.23 -0.96 0.1 -0.35 -1.17 1.11
121704 BRD-A51382177 YAPC 3.33 uM 24 h 0.0 0.0 0.0 -0.39 -1.31 1.71
129631 BRD-A51382177 HT29 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129660 BRD-A51382177 MCF??7.00 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129690 BRD-A51382177 PC3 0.25 uM 24 h 0.0 0.0 0.0 -0.47 -1.59 15.65
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).