CMap Candidate Details

Structure:
CMap ID: C12294
Pert ID: BRD-K31268420
Compound Name: NSC-693868
Targets: CDK5; GSK3A; CDK1
MoA: CDK inhibitor; GSK-3 inhibitor
SMILES: Nc1nnc2[nH]c3ccccc3nc12
InchiKey: DWHVZCLBMTZRQM-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1580 BRD-K31268420 HA1E 10 uM 24 h 0.0 0.0 0.0 -0.29 -0.99 0.5
2102 BRD-K31268420 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
2392 BRD-K31268420 PC3 10 uM 6 h 0.0 0.0 0.0 0.39 1.39 2.17
2622 BRD-K31268420 VCAP 10 uM 24 h 0.0 0.0 0.0 -0.37 -1.25 1.35
41763 BRD-K31268420 A375 10 uM 6 h 0.0 0.0 0.0 -0.29 -0.98 0.47
41929 BRD-K31268420 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
42351 BRD-K31268420 ASC 10 uM 24 h 0.0 0.0 0.0 0.27 0.97 0.35
42677 BRD-K31268420 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.22 0.79 0.07
42981 BRD-K31268420 HT29 10 uM 6 h -0.25 -1.05 0.23 -0.3 -1.02 0.6
43314 BRD-K31268420 MCF??7.00 10 uM 6 h -0.24 -0.98 0.12 0.25 0.9 0.22
43542 BRD-K31268420 NPC 10 uM 24 h 0.0 0.0 0.0 -0.38 -1.28 1.45
43840 BRD-K31268420 PHH 10 uM 24 h 0.0 0.0 0.0 0.27 0.95 0.32
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).