CMap Candidate Details

Structure:
CMap ID: C01230
Pert ID: BRD-A51393488
Compound Name: noscapine
Targets: SIGMAR1
MoA: Tubulin inhibitor; Bradykinin receptor antagonist
SMILES: COc1ccc2[C@H](OC(=O)c2c1OC)C1N(C)CCc2cc3OCOc3c(OC)c12
InchiKey: AKNNEGZIBPJZJG-ZVAWYAOSSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
2966 BRD-A51393488 HA1E 10 uM 6 h 0.2 0.83 0.0 0.24 0.85 0.14
3106 BRD-A51393488 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
3442 BRD-A51393488 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
3690 BRD-A51393488 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
39049 BRD-A51393488 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39274 BRD-A51393488 A549 10 uM 24 h 0.0 0.0 0.0 -0.26 -0.86 0.21
39572 BRD-A51393488 ASC 10 uM 24 h 0.0 0.0 0.0 0.28 0.99 0.4
39898 BRD-A51393488 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40181 BRD-A51393488 HT29 10 uM 6 h 0.2 0.81 0.0 0.0 0.0 0.0
40428 BRD-A51393488 MCF??7.00 10 uM 24 h 0.19 0.8 0.0 0.0 0.0 0.0
40700 BRD-A51393488 NEU 10 uM 24 h -0.22 -0.92 0.06 0.0 0.0 0.0
40998 BRD-A51393488 NPC 10 uM 24 h 0.0 0.0 0.0 -0.3 -1.01 0.58
41321 BRD-A51393488 SKB 10 uM 24 h -0.23 -0.98 0.12 -0.31 -1.04 0.66
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).