CMap Candidate Details

Structure:
CMap ID: C12324
Pert ID: BRD-K31339321
Compound Name: lirimilast
Targets: --
MoA: --
SMILES: CS(=O)(=O)Oc1ccc2c(NC(N)=O)c(oc2c1)C(=O)c1ccc(Cl)cc1Cl
InchiKey: YPFLFUJKZDAXRA-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
96810 BRD-K31339321 PC3 10 uM 24 h 0.0 0.0 0.0 0.23 0.82 0.1
121772 BRD-K31339321 HELA 3.33 uM 24 h 0.0 0.0 0.0 -0.27 -0.92 0.33
121803 BRD-K31339321 HT29 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121823 BRD-K31339321 MCF??7.00 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121872 BRD-K31339321 YAPC 0.37 uM 24 h 0.3 1.25 0.54 -0.36 -1.22 1.24
129766 BRD-K31339321 A375 2.22 uM 24 h -0.29 -1.21 0.58 -0.26 -0.87 0.23
129801 BRD-K31339321 HA1E 2.22 uM 24 h 0.0 0.0 0.0 -0.33 -1.11 0.91
129843 BRD-K31339321 HEK293 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129924 BRD-K31339321 JURKAT 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129969 BRD-K31339321 MCF10A 0.74 uM 24 h 0.0 0.0 0.0 0.26 0.92 0.26
130054 BRD-K31339321 MDAMB231 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130125 BRD-K31339321 THP1 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).