CMap Candidate Details

Structure:
CMap ID: C12325
Pert ID: BRD-K31342827
Compound Name: BRD-K31342827
Targets: --
MoA: --
SMILES: CN(C)CCCn1cc(C2=C(C(=O)NC2=O)c3c[nH]c4ccccc34)c5ccccc15
InchiKey: QMGUOJYZJKLOLH-UHFFFAOYSA-N
Compound Aliases: bisindolylmaleimide

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
6985 BRD-K31342827 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
8086 BRD-K31342827 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.3 1.07 0.63
8501 BRD-K31342827 PC3 10 uM 6 h 0.0 0.0 0.0 0.34 1.22 1.15
8808 BRD-K31342827 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
9405 BRD-K31342827 AGS 12 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
9714 BRD-K31342827 H1299 12 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10054 BRD-K31342827 HA1E 12 uM 6 h 0.0 0.0 0.0 0.29 1.04 0.56
10199 BRD-K31342827 HCC515 12 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
10500 BRD-K31342827 HCT116 12 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10772 BRD-K31342827 HEPG2 12 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
11467 BRD-K31342827 NCIH2073 12 uM 6 h 0.28 1.15 0.33 0.26 0.9 0.23
11747 BRD-K31342827 NCIH508 12 uM 6 h -0.25 -1.05 0.23 0.0 0.0 0.0
12030 BRD-K31342827 NCIH596 12 uM 6 h 0.0 0.0 0.0 -0.25 -0.85 0.2
12301 BRD-K31342827 NOMO1 12 uM 6 h 0.0 0.0 0.0 0.41 1.45 2.22
12775 BRD-K31342827 SW480 12 uM 6 h 0.0 0.0 0.0 0.26 0.92 0.25
13255 BRD-K31342827 U937 12 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
98751 BRD-K31342827 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
98886 BRD-K31342827 NEU 10 uM 24 h 0.0 0.0 0.0 0.38 1.33 1.72
99825 BRD-K31342827 U2OS 12 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
121884 BRD-K31342827 A375 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121951 BRD-K31342827 HEK293 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121977 BRD-K31342827 HELA 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122034 BRD-K31342827 HUVEC 10 uM 24 h 0.32 1.34 0.89 0.31 1.1 0.69
122085 BRD-K31342827 MCF10A 10 uM 24 h 0.22 0.9 0.03 0.0 0.0 0.0
122182 BRD-K31342827 THP1 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122209 BRD-K31342827 YAPC 10 uM 24 h 0.0 0.0 0.0 0.36 1.27 1.34
130312 BRD-K31342827 HT29 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130336 BRD-K31342827 JURKAT 0.03 uM 24 h 0.0 0.0 0.0 -0.33 -1.1 0.86
130441 BRD-K31342827 MDAMB231 2.22 uM 24 h 0.29 1.2 0.42 0.25 0.87 0.17
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).