CMap Candidate Details

Structure:
CMap ID: C12363
Pert ID: BRD-K31449336
Compound Name: BRD-K31449336
Targets: --
MoA: --
SMILES: COc1cccc(c1)c2cccc(c2)c3nc(cc4CN([C@H](CCO)c43)S(=O)C(C)(C)C)C(=O)NCCCN5CCOCC5
InchiKey: NZSCNZRATUWXGR-RMCGNSPKSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
59699 BRD-K31449336 VCAP 4 uM 24 h 0.22 0.9 0.02 0.0 0.0 0.0
85752 BRD-K31449336 A375 20 uM 24 h 0.22 0.9 0.03 -0.31 -1.04 0.67
85846 BRD-K31449336 A549 4 uM 24 h 0.0 0.0 0.0 -0.3 -1.02 0.61
85931 BRD-K31449336 HA1E 4 uM 24 h 0.0 0.0 0.0 -0.3 -1.02 0.62
86038 BRD-K31449336 HCC515 10 uM 24 h -0.23 -0.98 0.12 0.0 0.0 0.0
86146 BRD-K31449336 HEPG2 4 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
86251 BRD-K31449336 HT29 20 uM 24 h 0.0 0.0 0.0 0.25 0.9 0.22
86337 BRD-K31449336 MCF??7.00 4 uM 24 h 0.0 0.0 0.0 -0.23 -0.76 0.08
86422 BRD-K31449336 PC3 20 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
110159 BRD-K31449336 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).