CMap Candidate Details

Structure:
CMap ID: C12374
Pert ID: BRD-K31476763
Compound Name: AZD-9668
Targets: --
MoA: --
SMILES: Cc1c(cc(C(=O)NCc2ccc(cn2)S(C)(=O)=O)c(=O)n1-c1cccc(c1)C(F)(F)F)-c1ccnn1C
InchiKey: QNQZWEGMKJBHEM-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
121906 BRD-K31476763 A375 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121924 BRD-K31476763 A549 3.33 uM 24 h 0.2 0.84 0.0 0.0 0.0 0.0
121969 BRD-K31476763 HEK293 0.04 uM 24 h 0.0 0.0 0.0 -0.35 -1.17 1.14
122069 BRD-K31476763 HUVEC 1.11 uM 24 h 0.0 0.0 0.0 0.3 1.06 0.58
122119 BRD-K31476763 MCF??7.00 10 uM 24 h 0.25 1.05 0.16 -0.27 -0.92 0.34
122173 BRD-K31476763 PC3 0.04 uM 24 h 0.0 0.0 0.0 0.3 1.07 0.63
122224 BRD-K31476763 YAPC 0.04 uM 24 h 0.26 1.09 0.23 0.0 0.0 0.0
130242 BRD-K31476763 HA1E 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130303 BRD-K31476763 HELA 0.25 uM 24 h 0.0 0.0 0.0 0.31 1.11 0.71
130327 BRD-K31476763 HT29 0.08 uM 24 h 0.0 0.0 0.0 0.33 1.17 0.93
130370 BRD-K31476763 JURKAT 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130413 BRD-K31476763 MCF10A 0.08 uM 24 h 0.0 0.0 0.0 0.37 1.32 1.62
130460 BRD-K31476763 MDAMB231 0.74 uM 24 h 0.0 0.0 0.0 -0.31 -1.04 0.67
130502 BRD-K31476763 THP1 0.25 uM 24 h -0.35 -1.45 1.43 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).