CMap Candidate Details

Structure:
CMap ID: C12379
Pert ID: BRD-K31484631
Compound Name: rifabutin
Targets: --
MoA: --
SMILES: CO[C@H]1C=CO[C@@]2(C)Oc3c(C2=O)c2C4=NC5(CCN(CC(C)C)CC5)NC4=C(NC(=O)C(C)=C/C=C/[C@H](C)[C@H](O)[C@@H](C)[C@@H](O)[C@@H](C)[C@H](OC(C)=O)[C@@H]1C)C(=O)c2c(O)c3C
InchiKey: ATEBXHFBFRCZMA-DVAZEERGSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
33704 BRD-K31484631 A375 10 uM 6 h 0.0 0.0 0.0 -0.28 -0.93 0.34
33794 BRD-K31484631 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
34078 BRD-K31484631 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
34343 BRD-K31484631 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
34593 BRD-K31484631 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
35124 BRD-K31484631 HT29 10 uM 6 h 0.0 0.0 0.0 0.32 1.14 0.87
35310 BRD-K31484631 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
35762 BRD-K31484631 NPC 10 uM 24 h 0.26 1.1 0.24 0.19 0.68 0.01
35948 BRD-K31484631 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
36240 BRD-K31484631 PHH 10 uM 24 h 0.0 0.0 0.0 0.42 1.48 2.24
36533 BRD-K31484631 SKB 10 uM 24 h 0.2 0.84 0.0 0.0 0.0 0.0
36803 BRD-K31484631 VCAP 10 uM 24 h 0.0 0.0 0.0 -0.23 -0.76 0.07
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).