CMap Candidate Details

Structure:
CMap ID: C12436
Pert ID: BRD-K31627533
Compound Name: rimexolone
Targets: NR3C1
MoA: Glucocorticoid receptor agonist
SMILES: CCC(=O)[C@@]1(C)[C@H](C)C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@H]3[C@@H](O)C[C@]12C
InchiKey: QTTRZHGPGKRAFB-OOKHYKNYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
4412 BRD-K31627533 HCC515 10 uM 24 h 0.0 0.0 0.0 -0.34 -1.14 1.03
5070 BRD-K31627533 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39668 BRD-K31627533 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
39981 BRD-K31627533 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40788 BRD-K31627533 NEU 10 uM 24 h -0.22 -0.92 0.06 0.0 0.0 0.0
41089 BRD-K31627533 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41422 BRD-K31627533 SKB 10 uM 24 h 0.22 0.9 0.02 0.0 0.0 0.0
99829 BRD-K31627533 U2OS 6.66 uM 6 h 0.0 0.0 0.0 -0.25 -0.85 0.19
120513 BRD-K31627533 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120548 BRD-K31627533 A549 3.33 uM 24 h -0.25 -1.04 0.22 -0.41 -1.38 2.02
120592 BRD-K31627533 HA1E 0.125 uM 24 h 0.0 0.0 0.0 -0.37 -1.23 1.28
120649 BRD-K31627533 HT29 3.33 uM 24 h 0.0 0.0 0.0 -0.36 -1.2 1.18
120699 BRD-K31627533 JURKAT 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120771 BRD-K31627533 PC3 1.11 uM 24 h 0.0 0.0 0.0 0.33 1.17 0.93
120805 BRD-K31627533 YAPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129030 BRD-K31627533 HELA 0.25 uM 3 h -0.22 -0.92 0.06 -0.43 -1.46 15.35
129050 BRD-K31627533 MCF??7.00 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).