CMap Candidate Details

Structure:
CMap ID: C12439
Pert ID: BRD-K31633810
Compound Name: DAU-5884
Targets: CHRM3
MoA: Acetylcholine receptor antagonist
SMILES: CN1[C@H]2CC[C@@H]1C[C@@H](C2)OC(=O)N1Cc2ccccc2NC1=O
InchiKey: NWXCDQHBVVPPTL-WDNDVIMCSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
4215 BRD-K31633810 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
4561 BRD-K31633810 HCC515 10 uM 6 h 0.0 0.0 0.0 0.22 0.79 0.07
4675 BRD-K31633810 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
4919 BRD-K31633810 VCAP 10 uM 24 h 0.0 0.0 0.0 -0.29 -0.97 0.47
39117 BRD-K31633810 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39440 BRD-K31633810 A549 10 uM 6 h 0.23 0.94 0.06 -0.19 -0.63 0.01
39669 BRD-K31633810 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
39982 BRD-K31633810 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40257 BRD-K31633810 HT29 10 uM 6 h 0.0 0.0 0.0 -0.33 -1.1 0.87
40610 BRD-K31633810 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
41090 BRD-K31633810 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41423 BRD-K31633810 SKB 10 uM 24 h -0.25 -1.03 0.2 0.0 0.0 0.0
99830 BRD-K31633810 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).